Regenerative Medicine in Orthopaedics: Revolutionizing Healing with Stem Cells, BMAC, and PRP
Orthopaedic care is undergoing a transformation. Traditional treatments like surgery and medication are now being complemented—or even replaced—by regenerative medicine. These advanced therapies harness the body’s own healing potential to repair damaged tissues, reduce pain, and restore function. This post explores the most promising regenerative modalities in orthopaedics, including stem cell therapy for avascular necrosis (AVN), Bone Marrow Aspirate Concentrate (BMAC), Platelet-Rich Plasma (PRP), and more.
Stem Cell Therapy: A Game-Changer for Avascular Necrosis
Avascular necrosis (AVN), also known as osteonecrosis, is a condition where bone tissue dies due to lack of blood supply—commonly affecting the femoral head. If untreated, it can lead to joint collapse and the need for total hip replacement.
Stem cell therapy offers a non-surgical alternative by:
Clinical studies show that early-stage AVN responds well to stem cell injections, especially when combined with core decompression.
Bone Marrow Aspirate Concentrate (BMAC)
BMAC is a rich source of stem cells and growth factors extracted from the patient’s own bone marrow, typically from the iliac crest.
Applications in orthopaedics include:
BMAC is often used in combination with surgical procedures or injected directly into the affected joint or bone.
Platelet-Rich Plasma (PRP)
PRP therapy involves concentrating platelets from the patient’s blood and injecting them into injured tissues.
Benefits of PRP:
PRP is widely used for conditions like tennis elbow, rotator cuff injuries, and knee osteoarthritis.
Other Emerging Modalities
1. Amniotic Fluid Injections
2. Exosome Therapy
3. Prolotherapy
Who Can Benefit?
Regenerative therapies are ideal for:
However, patient selection and timing are critical. These therapies work best in early or moderate stages of disease and require expert evaluation.
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